Building Life Sciences Facilities for Operational Readiness and Long-Term Performance

Designing and delivering life sciences facilities requires more than technical expertise. Success depends on early planning, disciplined execution, and alignment across process development, facilities, and operations.  

In a recent podcast episode for Design, Build and Deliver, George Skillin, VP of Strategy Services at Project Farma, shares practical perspectives shaped by more than 35 years in biopharmaceutical manufacturing and capital project delivery. The conversation explores what manufacturers and owners should be prioritizing as they design, build, and scale GMP facilities in an increasingly complex market. 

Key themes include the critical role of upfront planning and scheduling to support speed and quality, as well as the importance of managing scope early to reduce costly changes during execution. George also discusses why operational readiness should begin during facility construction, not at the end of a project, and how early integration between process development and facility design sets teams up for successful startup and long-term performance.  

The discussion reflects on how the industry has evolved post-COVID, including increased investment in life sciences infrastructure, growing competition for experienced talent, and the rising importance of local workforce development. George also shares insights on emerging trends such as modular and prefabricated facilities, the practical realities of scaling manufacturing processes, and where AI is beginning to show potential in validation and commissioning, alongside its current limitations. 

For organizations planning new facilities, expanding capacity, or navigating complex capital projects, the episode offers a grounded view of what works in real-world life sciences manufacturing environments and where teams should focus to reduce risk and improve outcomes.  

Click here to listen to the podcast.